Prediction of outcome using pretreatment 18F-FDG PET/CT and MRI radiomics in locally advanced cervical cancer treated with chemoradiotherapy.
François LuciaDimitris VisvikisMarie-Charlotte DesseroitOmar MirandaJean-Pierre MalhairePhilippe RobinOlivier PradierMathieu HattUlrike SchickPublished in: European journal of nuclear medicine and molecular imaging (2017)
In LACC treated with CRT, radiomics features such as EntropyGLCM and GLNUGLRLM from functional imaging DWI-MRI and PET, respectively, are independent predictors of recurrence and loco-regional control with significantly higher prognostic power than usual clinical parameters. Further research is warranted for their validation, which may justify more aggressive treatment in patients identified with high probability of recurrence.
Keyphrases
- contrast enhanced
- locally advanced
- diffusion weighted
- diffusion weighted imaging
- rectal cancer
- magnetic resonance imaging
- computed tomography
- magnetic resonance
- neoadjuvant chemotherapy
- squamous cell carcinoma
- lymph node metastasis
- free survival
- high resolution
- radiation therapy
- phase ii study
- positron emission tomography
- heart failure
- clinical trial
- open label