Comprehensive Assessment of Colistin Induced Nephrotoxicity: Incidence, Risk Factors and Time Course.

Razan RabiAhmad EnayaMamoun W SweilehBanan M AieshAshraqat NamroutiZakaria I HamdanDina AbugaberZaher A Nazzal

Published in: Infection and drug resistance (2023)

Colistin-induced nephrotoxicity was a frequent issue associated with higher weights, mitigated by the combination with carbapenems. While higher colistin dosages, and earlier onset AKI, were linked to the progression to higher AKI stages and the need for dialysis.

Keyphrases

risk factors
escherichia coli
acinetobacter baumannii
pseudomonas aeruginosa
klebsiella pneumoniae
drug induced
multidrug resistant
gram negative
drug resistant
acute kidney injury
high glucose
diabetic rats
chronic kidney disease
cystic fibrosis
oxidative stress
end stage renal disease