Discordance of the Repeat GeneXpert MTB/RIF Test for Rifampicin Resistance Detection Among Patients Initiating MDR-TB Treatment in Uganda.
Willy SsengoobaJean de Dieu IragenaKevin KomakechIginitius OkelloJoanitah NalunjogiWinceslaus KatagiraIvan KimuliSusan AdakunMoses L JolobaGabriela TorreaBruce J KirengaPublished in: Open forum infectious diseases (2021)
Our findings show a high false-positive rifampicin resistance rate in low-TB burden patients, which calls for repeat testing in order to prevent unnecessary prescription of anti-MDR-TB therapy.
Keyphrases
- mycobacterium tuberculosis
- pulmonary tuberculosis
- end stage renal disease
- multidrug resistant
- newly diagnosed
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- stem cells
- patient reported outcomes
- mesenchymal stem cells
- replacement therapy
- label free
- cell therapy
- loop mediated isothermal amplification
- sensitive detection