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Leptin gene polymorphism (rs 7799039;G2548A) is associated with changes in lipid profile during a partial meal-replacement hypocaloric diet.

D PrimoO IzaolaDaniel-Antonio de Luis Roman
Published in: Journal of human nutrition and dietetics : the official journal of the British Dietetic Association (2020)
Subjects with an A allele of the rs7799039 variant in the LEPR gene showed a significant improvement in low-density lipoprotein-cholesterol and triglycerides levels after weight loss secondary to a pMR hypocaloric diet.
Keyphrases
  • weight loss
  • bariatric surgery
  • roux en y gastric bypass
  • gastric bypass
  • physical activity
  • genome wide
  • copy number
  • glycemic control
  • weight gain
  • dna methylation
  • transcription factor
  • genome wide analysis