Influence of sildenafil on esophageal motor function in humans: Studies using high-resolution manometry.

Ming-Wun WongJui-Sheng HungWei-Yi LeiChih-Hsun YiTso-Tsai LiuChien-Lin Chen

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2020)

Sildenafil attenuates EGJ barrier function, resting LES pressure, and LES relaxation. Both esophageal body contractility and contraction reserve are inhibited by sildenafil in healthy adults.

Keyphrases

pulmonary hypertension
pulmonary arterial hypertension
high resolution
smooth muscle
heart rate
heart rate variability
mass spectrometry
single molecule
blood pressure
tandem mass spectrometry
liquid chromatography