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Thermophoretic collection of virus-laden (SARS-CoV-2) aerosols.

A Xiangzhi ZhangB Jing WangC Chengbo WangD Zheng LianE Yong ShiF Yong RenG Yuying Yan
Published in: Biomicrofluidics (2021)
Detecting the existence of SARS-CoV-2 in the indoor atmosphere is a practical solution to track the prevalence and prevent the spread of the virus. In this work, a thermophoretic approach is presented to collect the novel coronavirus-laden aerosols from the air and accumulate to high concentrations adequate for the sensitivity of viral RNA detection. Among the factors, the density and particle size have negligible effects on particle trajectory, while the vertical coordinates of particles increase with the rise in heating source temperature. When the heating temperature is higher than 355 K , all of the particles exit the channel from one outlet; thus, the collecting and accumulating of virus-laden aerosols can be realized. This study provides a potential approach to accelerate the detection of SARS-CoV-2 and avoid a false negative in the following RNA test.
Keyphrases
  • sars cov
  • respiratory syndrome coronavirus
  • water soluble
  • loop mediated isothermal amplification
  • real time pcr
  • risk factors
  • label free
  • climate change
  • sensitive detection
  • human health