Has the introduction of direct oral anticoagulants (DOACs) in England increased emergency admissions for bleeding conditions? A longitudinal ecological study.
Ana AlfirevicJennifer DowningKonstantinos DarasTerence ComerfordMunir PirmohamedBen BarrPublished in: BMJ open (2020)
Our data show that the rapid increase in prescribing of DOACs after changes in National Institute for Health and Care Excellence guidelines in 2014 may have been associated with a higher rate of emergency admissions for bleeding conditions. These consequences need to be considered in assessing the benefits and costs of the widespread use of DOACs.
Keyphrases
- direct oral anticoagulants
- atrial fibrillation
- healthcare
- venous thromboembolism
- public health
- emergency department
- quality improvement
- primary care
- palliative care
- mental health
- human health
- climate change
- clinical practice
- health information
- machine learning
- emergency medical
- risk assessment
- pain management
- loop mediated isothermal amplification
- data analysis
- adverse drug