Development of a multi-functional concurrent assay using weak cation-exchange solid-phase extraction (WCX-SPE) and reconstitution with a diluted sample aliquot for anti-doping analysis.
Yongseok KimMijin JeonHophil MinJunghyun John SonJaeick LeeOh-Seung KwonMyeong Hee MoonKi Hun KimPublished in: Rapid communications in mass spectrometry : RCM (2018)
The method was validated and applied to real samples in accordance with the external quality assessment scheme of WADA and to the previously reported samples that had provided positive test results. This novel method using hybrid sample preparation and LC/MS could be useful to screen multiple classes of the 264 targeted substances in anti-doping analysis.