Platelet-derived exosomes promote neutrophil extracellular trap formation during septic shock.

Yang JiaoWeiwei LiWei WangXingyu TongRan XiaJie FanJianer DuChengmi ZhangXueyin Shi

Published in: Critical care (London, England) (2020)

Platelet-derived exosomes promote excessive NET formation in sepsis and subsequent organ injury. This finding suggests a previously unidentified role of platelet-derived exosomes in sepsis and may lead to new therapeutic approaches.

Keyphrases

septic shock
mesenchymal stem cells
stem cells
intensive care unit
acute kidney injury
bone marrow
weight gain