Activation of CD8+ T Cells in COPD Lung.

Ana B Villaseñor-AltamiranoDhawal JainYunju JeongJaivardhan A MenonMari KamiyaHibah HaiderReshmi ManandharMuhammad Dawood Amir SheikhHumra AtharLouis T MerriamMin Hyung RyuTakanori SasakiPeter J CastaldiDeepak A RaoLynette M ShollMarina ViveroCraig P HershXiaobo ZhouJustus VeerkampJeong H YunEdy Y Kimnull null

Published in: American journal of respiratory and critical care medicine (2023)

CD8+ TEMRA cells are increased in mild-moderate COPD lung and may contribute to inflammation that precedes severe disease. Further study of these CD8+T cells may have therapeutic implications for preventing severe COPD.

Keyphrases

chronic obstructive pulmonary disease
lung function
induced apoptosis
early onset
oxidative stress
cell cycle arrest
cystic fibrosis
high intensity
drug induced
cell death
signaling pathway