Zeaxanthin Induces Apoptosis via ROS-Regulated MAPK and AKT Signaling Pathway in Human Gastric Cancer Cells.
Ya-Nan ShengYing-Hua LuoShao-Bin LiuWan-Ting XuYu ZhangTong ZhangHui XueWen-Bo ZuoYan-Nan LiChang-Yuan WangCheng-Hao JinPublished in: OncoTargets and therapy (2020)
Zeaxanthin has a potential effect against gastric cancer cells through the ROS-mediated MAPK, AKT, NF-κB, and STAT3 signaling pathways, and it is expected to become a new drug for the treatment of human gastric cancer.
Keyphrases
- signaling pathway
- pi k akt
- endothelial cells
- induced apoptosis
- epithelial mesenchymal transition
- cell death
- induced pluripotent stem cells
- dna damage
- cell proliferation
- reactive oxygen species
- transcription factor
- risk assessment
- inflammatory response
- toll like receptor
- human health
- combination therapy
- endoplasmic reticulum stress
- drug induced