Beyond Early LDL Cholesterol Lowering to Prevent Coronary Atherosclerosis in Familial Hypercholesterolemia.

Shirin IbrahimLaurens F ReeskampJim N de GoeijG Kees HovinghR Nils PlankenWillem A BaxJames K MinJames P EarlsPaul KnaapenAlbert WiegmanErik S G StroesNick S Nurmohamed

Published in: European journal of preventive cardiology (2024)

Lifetime exposure to LDL-C determines coronary plaque burden in FH, underlining the need of early as well as potent treatment initiation. Periodic CCTA may offer a unique opportunity to monitor coronary atherosclerosis and personalize treatment in FH.

Keyphrases

coronary artery disease
coronary artery
cardiovascular disease
low density lipoprotein
aortic stenosis
transcatheter aortic valve replacement
left ventricular
replacement therapy