The Silk Protein Sericin Promotes Viability of ARPE-19 and Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelial Cells in vitro.

Ayyad Zartasht KhanTor Paaske UtheimMorten Carstens MoeHans Christian D AassDipak SapkotaEvan Michael VallenariJon Roger Eidet

Published in: Current eye research (2020)

This is the first study to demonstrate that supplementing the culture media with sericin promotes the viability of iPSC-RPE and ARPE-19. Sericin's viability-promoting effects may have important implications for retinal therapeutics and regenerative medicine research.

Keyphrases

optical coherence tomography
high glucose
small molecule
diabetic rats
drug induced
endothelial cells
oxidative stress
optic nerve
wound healing