Validation of a paraoxon-based method for measurement of paraoxonase (PON-1) activity and establishment of RIs in horses.

This study demonstrated that the analytic performances of the paraoxon-based method for measurement of PON-1 in horses are acceptable. The PON-1 activity is lower in horses than in other domestic species. These results may provide a basis for further studies designed to establish whether healthy and sick horses can be correctly classified by using the PON-1 assay.