Integrating Signaling Pathways with Transcription Factor Networks-On the Trail of Sisyphus?
Kostas A PapavassiliouDonatella Delle CavePublished in: Biomolecules (2024)
In the context of health and disease research, cells use signaling pathways that transduce stimuli from the extracellular environment to modulate intracellular gene expression via the activity of transcription factors and cofactors (coactivators and/or corepressors) [...].
Keyphrases
- transcription factor
- induced apoptosis
- signaling pathway
- gene expression
- pi k akt
- cell cycle arrest
- dna binding
- healthcare
- public health
- endoplasmic reticulum stress
- dna methylation
- mental health
- epithelial mesenchymal transition
- oxidative stress
- health information
- genome wide identification
- reactive oxygen species
- health promotion
- climate change