Imaging Net Retrograde Axonal Transport In Vivo: A Physiological Biomarker.

Pin-Tsun Justin LeeZachary KennedyYuzhen WangYimeng LuCarolina CefalielloÖzgün UyanChun-Qing SongBruno Miguel da Cruz GodinhoZuoshang XuMary RusckowskiWen XueRobert H Brown

Published in: Annals of neurology (2022)

This assay of net retrograde axonal transport has broad potential clinical applications and should be particularly valuable as a physiological biomarker that permits early detection of benefit from potential therapies for motor neuron diseases. ANN NEUROL 2022;91:716-729.

Keyphrases

spinal cord injury
high resolution
high throughput
optic nerve
risk assessment
photodynamic therapy
single cell
climate change
fluorescence imaging