Network reconstruction of the mouse secretory pathway applied on CHO cell transcriptome data.

Anne Mathilde LundChristian Schrøder KaasJulian BrandlLasse Ebdrup PedersenHelene Faustrup KildegaardClaus KristensenMikael Rørdam Andersen

Published in: BMC systems biology (2017)

The RECON of the secretory pathway represents a strong tool for interpretation of data related to protein secretion as illustrated with transcriptomic data of Chinese Hamster Ovary (CHO) cells, the main platform for mammalian protein production.

Keyphrases

single cell
electronic health record
big data
gene expression
protein protein
amino acid
high throughput
stem cells
genome wide
data analysis
binding protein
cell proliferation