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Inhibition of post-surgery tumour recurrence via a sprayable chemo-immunotherapy gel releasing PD-L1 antibody and platelet-derived small EVs.

Jian ZhaoHao YeQi LuKaiyuan WangXiaofeng ChenJiaxuan SongHelin WangYutong LuMaosheng ChengZhonggui HeYinglei ZhaiHaotian ZhangJin Sun
Published in: Journal of nanobiotechnology (2022)
Our findings indicated that the immunotherapeutic fibrin gel could "awaken" the host innate immune system to inhibit both local tumour recurrence post-surgery and metastatic potential, thus, it could serve as a promising approach to prevent tumour recurrence.
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