Single nucleotide variants around the connective tissue growth factor (CTGF/CCN2) gene and their association with multiple sclerosis risk, disability scores, and rate of disease progression.

Birsen Can Demirdöğen Osman Oğuzhan Kılıç Elif Naz Karagülle Latife Mekselina Kalmaz Semra Mungan

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2022)

To our knowledge, this is the first evidence of the involvement of variants around the CTGF gene in MS risk and disability progression.

Keyphrases

multiple sclerosis
growth factor
copy number
genome wide
white matter
healthcare
mass spectrometry
ms ms
genome wide identification
gene expression
dna methylation