HSP90 inhibition acts synergistically with heat to induce a pro-immunogenic form of cell death in colon cancer cells.

Petros X E Mouratidis Gail Ter Haar

Published in: International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group (2021)

Sub-ablative heating can act synergistically with the clinically relevant HSP90 inhibitor NVP-AUY922 to induce a pro-immunogenic form of cell death in colon cancer cells.

Keyphrases

cell death
heat stress
heat shock protein
heat shock
anti inflammatory
cell cycle arrest
oxidative stress
cell proliferation
signaling pathway