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RAS-associated Autoimmune Leukoproliferative disease (RALD) manifested with early-onset SLE-like syndrome: a case series of RALD in Chinese children.

Wei WangYu ZhouLinqing ZhongLin WangXiaoyan TangMingsheng MaJi LiHong-Mei Song
Published in: Pediatric rheumatology online journal (2019)
For those early-onset SLE-like patients with predominant hematologic disorders, monocytosis, recurrent infectious history, accompanied with hepatosplenomegaly and lymphadenopathy, a genetic screening of PIDs might be required.
Keyphrases
  • early onset
  • systemic lupus erythematosus
  • late onset
  • disease activity
  • young adults
  • multiple sclerosis
  • genome wide
  • rheumatoid arthritis
  • case report
  • copy number
  • wild type
  • dna methylation