Association between opioid usage and rectal dysfunction in constipation: A cross-sectional study of 2754 patients.

Paul F VollebregtRichard L HooperAdam Donald FarmerJonjo MillerCharles H KnowlesS Mark Scott

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2020)

Opioid use is over-represented in patients referred for investigation of constipation. Opioids for moderate-severe pain are associated with rectal sensorimotor abnormalities. Further studies are required to determine whether this association indicates causation.

Keyphrases

end stage renal disease
chronic pain
ejection fraction
newly diagnosed
pain management
chronic kidney disease
peritoneal dialysis
oxidative stress
rectal cancer
abdominal pain