Relationship Between Genotype Status and Clinical Outcome in Hypertrophic Cardiomyopathy.
Jiri BonaventuraEthan J RowinRaymond H ChanMichael Thomas ChinVeronika PuchnerovaEva PolakováMilan MacekPavel VotýpkaRebecca A BatorskyGayani PereraBenjamin KoetheJosef VeselkaBarry J MaronMartin S MaronPublished in: Journal of the American Heart Association (2024)
In this large consecutive cohort of patients with HCM, genotype (G+ or G-) was not a predictor of clinical course, including all-cause and HCM-related mortality and risk for heart failure progression or sudden death. G+ status should not be used to dictate clinical management or predict outcome in HCM.