AQP1 Promoter Variant, Water Transport, and Outcomes in Peritoneal Dialysis.
Johann MorelleCéline MarechalZanzhe YuHuguette DebaixTanguy CorreMark LambieMarion VerduijnFriedo DekkerPhilippe BovyPieter EvenepoelBert BammensRafael SelgasMaria A BajoAnnemieke M CoesterAmadou SowNicolas HautemDirk G StruijkRaymond T KredietJean-Luc BalligandEric GoffinRalph CrottPierre RipocheSimon DaviesOlivier DevuystPublished in: The New England journal of medicine (2021)
A common variant in AQP1 was associated with decreased ultrafiltration and an increased risk of death or technique failure among patients treated with peritoneal dialysis. (Funded by the Swiss National Science Foundation and others.).