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The pharmacological properties of 3-arm or 4-arm DOTA constructs for conjugation to α-melanocyte-stimulating hormone analogues for melanoma imaging.

Masato KobayashiToshitaka KatoKohshin WashiyamaMasaaki IharaAsuka MizutaniKodai NishiLeo G FloresRyuichi NishiiKeiichi Kawai
Published in: PloS one (2019)
The 4-arm DOTA construct has better chemical properties for peptide radiotracers than the 3-arm DOTA construct.
Keyphrases
  • pet ct
  • pet imaging
  • high resolution
  • molecular docking
  • computed tomography
  • positron emission tomography
  • mass spectrometry