Homologous PB1 gene promotes the replication efficiency of avian influenza H7N4 candidate vaccine virus.
Liqi LiuZi LiJianfang ZhouJia LiuXiyan LiWeijuan HuangNing XiaoDa-Yan WangPublished in: Influenza and other respiratory viruses (2022)
Homologous PB1 of the H7N4 virus improves the growth ability while sustaining low pathogenicity. Collectively, the gene composition of the (5 + 3) reassortant virus is a suitable H7N4 CVV for potential pandemic preparedness.