Biomarker Inference and the Timing of Next-Generation Sequencing in a Multi-Institutional, Cross-Cancer Clinicogenomic Data Set.

Kenneth L Kehl Jessica A Lavery Samantha Brown Hannah E Fuchs Gregory J Riely Deborah SchragAshley NewcombChelsea NicholsChristine M Micheel Philippe L BedardShawn M SweeneyMichael FiandaloKatherine S Panageasnull null

Published in: JCO precision oncology (2024)

To evaluate the appropriateness of a data set for a particular research question, it is crucial to measure associations between dynamic cancer status and the timing of NGS, as well as to evaluate interactions involving biomarkers of interest and NGS timing with respect to survival outcomes.

Keyphrases

papillary thyroid
squamous cell
electronic health record
big data
copy number
single cell
young adults
dna methylation