Modeling Doxorubicin-Induced Cardiomyopathy With Fibrotic Myocardial Damage in Wistar Rats.

Ekaterina PodyachevaTatiana ShmakovaEkaterina KushnarevaAnatoliya OnopchenkoMikhail MartynovDaria Andreeva Roman Toropov Yuri CheburkinKsenia LevchukAlexandra GoldaevaYana G Toropova

Published in: Cardiology research (2022)

We assume that cumulative dose of 10 mg/kg with a frequency of administration of six times in 2 days can be used to study the mechanisms of anthracycline cardiomyopathy development.

Keyphrases

heart failure
oxidative stress
drug delivery
left ventricular
diabetic rats
systemic sclerosis
idiopathic pulmonary fibrosis
cancer therapy
drug induced
endothelial cells