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Hyperbaric effects on cold stored whole blood following a military dive mission profile.

Christopher J ScheiberChad M SpencerRichard D NeadingMichael P O'ConnellCasey F BeckerTyler R ScarboroughJeremy D HorseyJoshua A PerezBaron J OchoaMichael A WilkinsonPasha BentleyJansen N SeheultMichael L BoisenMark H Yazer
Published in: Transfusion (2022)
These data suggest that pressurization of WB up to 5 atm did not impact parameters tested. Changes observed in lactate and platelet count need further study, as well as complementary testing of red blood cell integrity. Further investigation of the hyperbaric extremes is necessary to determine if there is a damage inducing pressure to which WB should not be exposed.
Keyphrases
  • red blood cell
  • dna damage
  • oxidative stress
  • dna repair
  • big data
  • room temperature
  • dna damage response
  • data analysis