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Oral implant osseointegration model in C57Bl/6 mice: microtomographic, histological, histomorphometric and molecular characterization.

Claudia Cristina BiguettiFranco CavallaElcia M SilveiraAngélica Cristina FonsecaAndreia Espindola VieiraAndre Petenuci TabanezDanieli C RodriguesAna Paula Favaro TromboneGustavo Pompermaier Garlet
Published in: Journal of applied oral science : revista FOB (2018)
This study demonstrated a unique molecular view of oral osseointegration kinetics in C57Bl/6 mice, evidencing potential elements responsible for orchestrating cell migration, proliferation, ECM deposition and maturation, angiogenesis, bone formation and remodeling at the bone-implant interface in parallel with a novel microscopic analysis.
Keyphrases
  • cell migration
  • soft tissue
  • high fat diet induced
  • endothelial cells
  • signaling pathway
  • bone mineral density
  • insulin resistance
  • type diabetes
  • adipose tissue
  • human health