Age-dependent effect of metabolic phenotypes on carotid atherosclerotic disease in coronary heart disease patients (CORDIOPREV study).
Francisco Miguel Gutierrez-MariscalAntonio García-RíosPurificación Gómez-LunaCarolina Fernández-GandaraMagdalena P CardeloSilvia de la Cruz-AresFernando Rodriguez-CantalejoRaul M LuqueAna León-AcuñaJavier Delgado-ListaPablo Perez-MartinezElena Maria Yubero-SerranoJose Lopez-MirandaPublished in: BMC geriatrics (2020)
Our results suggest that CHD patients aged≥60 are less metabolic flexible compared to patients aged< 60. Thus, MHO patients aged≥60 show the same risk of suffering carotid atherosclerosis as those with metabolic disease, while MHO patients aged< 60 show lower risk than MSO. This fact indicates the need to focus on therapeutic strategies in order to modify those parameters related to obesity and metabolic inflexibility in patients with CHD before entering old age.