Neoadjuvant therapy does not impact the biliary microbiome in patients with pancreatic cancer.
Shay BehrensThomas Lee SuttonRanish K PatelIssac R SchwantesJack O'GradyAlicia JohnsonAaron GrossbergCharles LopezErin GilbertSkye MayoBrett C SheppardPublished in: Journal of surgical oncology (2023)
Biliary stenting is the greatest predictor for positive biliary cultures and SSIs in resected PDAC patients. Neither NAC nor radiotherapy impact bile culture positivity, speciation, rates, or antibiotic resistance patterns, and perioperative antibiotic prophylaxis should not differ.
Keyphrases
- end stage renal disease
- lymph node
- newly diagnosed
- locally advanced
- ejection fraction
- chronic kidney disease
- prognostic factors
- rectal cancer
- squamous cell carcinoma
- patients undergoing
- transcription factor
- early stage
- stem cells
- acute kidney injury
- patient reported outcomes
- radiation induced
- percutaneous coronary intervention