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ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts.

Alice L YuanChristian B RicksAlexandra K BohmXueqing LunLori MaxwellShahana SafdarShazreh BukhariAmanda GerberWajid SayeedElizabeth A BeringHaley PedersenJennifer A ChanYaoqing ShenMarco MarraDavid R KaplanWarren MasonLindsey D GoodmanRavesanker EzhilarasanAscher B KaufmannMatthew CabralSteve M RobbinsDonna L SengerDaniel P CahillErik P SulmanJ Gregory CairncrossMichael D Blough
Published in: PloS one (2018)
In laboratory models, the addition of ABT-888 to TMZ overcame resistance to TMZ.
Keyphrases
  • newly diagnosed