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Arrestin beta-2 deficiency exacerbates periodontal inflammation by mediating activating transcription factor 6 activation and abnormal remodelling of the extracellular matrix.

Meiting FengRuiling WangLi DengYanan YangSiying XiaFeng LiuLijun Luo
Published in: Journal of clinical periodontology (2024)
ARRB2 mediates ECM remodelling via inhibition of the ATF6 signalling pathway, which ultimately exerts a protective effect on periodontal tissues.
Keyphrases
  • extracellular matrix
  • transcription factor
  • oxidative stress
  • gene expression
  • signaling pathway
  • endoplasmic reticulum stress
  • replacement therapy
  • genome wide identification