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Early-Onset Hydroxychloroquine Retinopathy and a Possible Relationship to Blood Levels: Comment on the Article by Petri et al.

Naoto YokogawaAkiko Ohno-TanakaMasayuki HashiguchiMikiko ShimizuHiroko OzawaShinji UenoKei ShinodaDavid J Browning
Published in: Arthritis & rheumatology (Hoboken, N.J.) (2021)
Petri et al reported that higher hydroxychloroquine (HCQ) blood levels predicted later retinopathy (1) . However, in a recent case-control study, the blood level was not associated with retinopathy(2). The inconsistency may arise from dose adjustment over the years and the timing of blood level testing.
Keyphrases
  • early onset
  • late onset