Digital image analysis of HER2 immunohistochemistry in gastric- and oesophageal adenocarcinoma: a validation study on biopsies and surgical specimens.

Timco KoopmanGeertruida H de BockHenk J BuikemaMaria M SmitsMaarten LouwenMariska HageAlex L T ImholzBert Van der Vegt

Published in: Histopathology (2017)

DIA is a reliable and feasible alternative to manual HER2 IHC scoring in gastro-oesophageal adenocarcinoma, both in biopsies and surgical specimens, leading to a reduction of 2+ cases for which subsequent ISH testing is required.

Keyphrases

squamous cell carcinoma
ultrasound guided
locally advanced
fine needle aspiration
radiation therapy
rectal cancer