Effects of myocardial ischemia/reperfusion injury on plasma metabolomic profile during aging.

Claudio De LuciaMichela PiedepalumboLu WangFausto Carnevale NetoDaniel RafteryErhe GaoDomenico Pratico Daniel E L Promislow Walter J Koch

Published in: Aging cell (2020)

Our approach increases our understanding of age-associated plasma metabolomic signatures in mice with and without heart disease excluding confounding factors related to metabolic comorbidities.

Keyphrases

ischemia reperfusion injury
oxidative stress
left ventricular
pulmonary hypertension
genome wide
heart failure
gene expression
metabolic syndrome
dna methylation
skeletal muscle