Towards precision dosing of aripiprazole in children and adolescents with autism spectrum disorder: linking blood levels to weight gain and effectiveness.

Rebecca A HermansS D T SassenSanne Maartje KloosterboerC G ReichartM E J KouijzerM M J de KroonD BastiaansenD van AltenaR H N van SchaikKazem NasserinejadM H J HillegersBirgit C P KochB DierckxB C M de Winter

Published in: British journal of clinical pharmacology (2023)

Our results indicate a threshold with regard to safety, which suggests that therapeutic drug monitoring of aripiprazole could potentially increase safety in children and adolescents with ASD and behavioral problems.

Keyphrases

weight gain
body mass index
birth weight
mental health
autism spectrum disorder
systematic review
weight loss
attention deficit hyperactivity disorder
preterm birth
intellectual disability
gestational age