Azulene-based fluorescent chemosensor for adenosine diphosphate.

Carlos M Lopez-AlledSang Jun ParkDong Joon LeeLloyd C Murfin Gabriele I Kociok-Köhn Jodie L Hann Jannis Wenk Tony David James Hwan Myung Kim Simon E Lewis

Published in: Chemical communications (Cambridge, England) (2021)

AzuFluor® 435-DPA-Zn, an azulene fluorophore bearing two zinc(II)-dipicolylamine receptor motifs, exhibits fluorescence enhancement in the presence of adenosine diphosphate. Selectivity for ADP over ATP, AMP and PPi results from appropriate positioning of the receptor motifs, since an isomeric sensor cannot discriminate between ADP and ATP.

Keyphrases

protein kinase
quantum dots
heavy metals
single molecule
binding protein
protein protein
risk assessment
oxide nanoparticles
energy transfer