Topical Delivery of Nivolumab, a Therapeutic Antibody, by Fractional Laser and Pneumatic Injection.
Rikke Louise ChristensenSilje H OmlandDaniel Pergament PerssonSøren HustedMerete HaedersdalUffe Hoegh OlesenPublished in: Lasers in surgery and medicine (2020)
AFL-assisted passive diffusion and immediate EPI-assisted delivery show the potential to deliver therapeutic antibodies locally. Future in vivo and pharmacokinetic studies would reveal the full potential for topical antibody delivery by energy-based devices. Lasers Surg. Med. © 2020 Wiley Periodicals LLC.