Integrated proteotranscriptomics of breast cancer reveals globally increased protein-mRNA concordance associated with subtypes and survival.
Wei TangMing ZhouTiffany H DorseyDaRue A PrietoXin W WangEytan RuppinTimothy D VeenstraStefan AmbsPublished in: Genome medicine (2018)
Our study provides new insights into the relationship between protein and mRNA expression in breast cancer and shows that an integrated analysis of the proteome and transcriptome has the potential of uncovering novel disease characteristics.