Reduced microglia activity in patients with long-term immunosuppressive therapy after liver transplantation.

Meike DirksRalph BuchertAnn-Katrin WirriesHenning PflugradGerrit M GrosseCarlotta PetruschChristian SchützeFlorian WilkeMartin MamachLinda HamannLaura B N LangerXiao-Qi DingHannelore Barg-HockJürgen KlempnauerChristian H WetzelMario LukacevicEike JanssenMariella KesslerFrank M BengelLilli GeworskiRainer RupprechtTobias L RossGeorg BerdingKarin Weissenborn

Published in: European journal of nuclear medicine and molecular imaging (2021)

Our results provide evidence of chronic suppression of microglial activity in liver-transplanted patients under CNI therapy especially in patients with high sensitivity to CNI toxicity.

Keyphrases

end stage renal disease
inflammatory response
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors
oxidative stress
lipopolysaccharide induced
patient reported outcomes
spinal cord
spinal cord injury
bone marrow
drug induced