Genome-Wide Genetic Associations Prioritize Evaluation of Causal Mechanisms of Atherosclerotic Disease Risk.

Thomas Quertermous Daniel Yuhang Li Chad S Weldy Markus Ramste Vinod ScariaJoão P MonteiroWenduo Gu Matthew D Worssam Brian T PalmisanoChong Y ParkPaul Cheng

Published in: Arteriosclerosis, thrombosis, and vascular biology (2024)

Genome-wide association studies represent a paradigm shift in the study of cardiovascular disease, providing identification of genes, cellular phenotypes, and disease pathways that empower the future of targeted drug development.

Keyphrases

genome wide
cardiovascular disease
genome wide association
dna methylation
copy number
bioinformatics analysis
type diabetes
current status
cancer therapy
drug delivery
transcription factor
cardiovascular events
cardiovascular risk factors