Chaperone-Mediated Autophagy Controls Proteomic and Transcriptomic Pathways to Maintain Glioma Stem Cell Activity.

Jaione Auzmendi-IriarteMaddalen Otaegi-UgartemendiaEstefania Carrasco-GarciaMikel AzkargortaAntonio DiazAnder Saenz-AntoñanzasJoaquin Andrés Andermatten Mikel Garcia-PugaIdoia GarciaAlejandro Elua-PininIrune RuizNicolas SampronFélix ElortzaAna Maria CuervoAnder Matheu

Published in: Cancer research (2022)

A receptor of chaperone-mediated autophagy regulates glioblastoma stem cells and may serve as a potential biomarker for advanced tumor grade and poor survival in this disease.

Keyphrases

stem cells
cell death
endoplasmic reticulum stress
signaling pathway
oxidative stress
heat shock protein
heat shock
endoplasmic reticulum
cell therapy
binding protein
free survival
mesenchymal stem cells