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Statins, metformin, and RAS inhibitors did not reduce variceal bleeding risk and mortality in a large, real-life cohort of patients with cirrhosis.

Nikolaus PfistererMichael SchwarzCaroline SchmidbauerFlorian PutreLukas RittFlorian RiedlLukas HartlMathias JachsMattias MandorferChristian MadlMichael TraunerThomas Reiberger
Published in: PloS one (2024)
In clinical practice, variceal bleeding and mortality rates of cirrhotic patients were not reduced by co-medication with statins, metformin or RASi. Nevertheless, we recommend the use of these co-medications by indication, as they may still exert beneficial effects on non-bleeding complications in patients with liver cirrhosis.
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