Acute pain-related depression of operant responding maintained by social interaction or food in male and female rats.

A N BaldwinM L BanksS A MarshE A TownsendM VenniroY ShahamS Stevens Negus

Published in: Psychopharmacology (2022)

Operant responding maintained by social interaction was more sensitive to pain-related disruption and less responsive to opioid analgesic rescue than food-maintained operant responding. Social behavior may be especially vulnerable to depression by pain states.

Keyphrases

chronic pain
pain management
neuropathic pain
healthcare
mental health
depressive symptoms
liver failure
spinal cord
sleep quality
spinal cord injury
drug induced
postoperative pain
intensive care unit
drug delivery
physical activity
acute respiratory distress syndrome
aortic dissection
mechanical ventilation