Moderate intensity exercise in hypoxia increases IGF-1 bioavailability and serum irisin in individuals with type 1 diabetes.

Aleksandra ŻebrowskaMarcin SikoraAnna KonarskaAnna ZwierzchowskaTomasz KamińskiAnna RobinsBarbara Hall

Published in: Therapeutic advances in endocrinology and metabolism (2020)

The study results suggest that moderate intensity continuous Ex has beneficial effect on BDNF and IGF-1 levels. Ex in hypoxic conditions may be more effective in increasing availability of IGF-1. The alterations in the post-Ex irisin levels and IGF-1 system may be contributing to more effective glycaemia control in patients with T1D.

Keyphrases

high intensity
pi k akt
binding protein
growth hormone
resistance training
endothelial cells
cell proliferation
stress induced