The potential role of precision medicine to alleviate racial disparities in prostate, bladder and renal urological cancer care.
Kunal K SindhuZachary S DoveyMarcher ThompsonAnthony D NehlsenKarin A SkalinaBeata MalachowskaShaakir HasanChandan GuhaJustin TangLucas Resende SalgadoPublished in: BJUI compass (2024)
For all GU cancers, the historical underrepresentation of ethnic minorities in clinical trials still exists and there is an urgent need for recruitment strategies to address this. PM is a promising development with the potential to reduce inequities in GU cancers, however, both improved understanding of race-specific tumour biology, and enhanced recruitment of minority populations into clinical trials are required. Without this, the benefits of PM will be limited.
Keyphrases
- clinical trial
- particulate matter
- air pollution
- polycyclic aromatic hydrocarbons
- prostate cancer
- heavy metals
- phase ii
- urinary tract
- spinal cord injury
- water soluble
- open label
- double blind
- phase iii
- study protocol
- human health
- african american
- childhood cancer
- genetic diversity
- healthcare
- affordable care act
- placebo controlled