Pregnancy Complicated by the Most Frequent Forms of Maturity Onset Diabetes of the Young: A Narrative Review on Its Pharmacological Implications.

Claudio Daniel GonzalezVictoria Insussarry PerkinsAgustina Alves de LimaRocio FogarGustavo D FrechtelGuillermo Di Girolamo

Published in: Current reviews in clinical and experimental pharmacology (2022)

The impact of changes in the pharmacological behavior of drugs like SU and other metabolized/transported by mechanisms altered in a pregnancy complicated by MODY is unknown. However, switching-to-insulin recommendation formulated for MODY 1 and 3 seems to be justified. Further research in this field is needed for a better understanding of changes in drug activity associated with this particular subset of patients with MFD.

Keyphrases

type diabetes
preterm birth
glycemic control
pregnancy outcomes
cardiovascular disease
middle aged
emergency department
drug induced
pregnant women