Effect of traditional chinese medicine (TCM) and its fermentation using Lactobacillus plantarum on ceftriaxone sodium-induced dysbacteriotic diarrhea in mice.

Xin GuoZipeng YanJixiang WangXinfeng FanJie KangRuiyan NiuZilong Sun

Published in: Chinese medicine (2022)

TCM, LP, and TCM fermented with LP alleviated CS-induced diarrhea symptoms, and improved the intestinal flora and barrier function. Four compounds including (S)-(-)-2-hydroxyisocaproic acid, L-methionine, 4GBA, and PLA in FSD, which were identified by UHPLC-Q-TOF/MS, might function in modulating intestinal flora and improving villi structure.

Keyphrases

high glucose
diabetic rats
ms ms
drug induced
irritable bowel syndrome
signaling pathway
type diabetes
clostridium difficile
oxidative stress
metabolic syndrome
mass spectrometry
simultaneous determination
sleep quality
saccharomyces cerevisiae
liquid chromatography